Caas A-Valve can assist physicians during or in preparation of valve replacements as TAVR procedures.
- Caas A-Valve
CAAS A-Valve assists the physician in evaluating aortic regurgitation after transcatheter valve replacement.
The qRA workflow (also called videodensitometry, VD-AR, LVOT-AR) enables the physician to quantify valvular and paravalvular regurgitation immediately in the cathlab directly after placing the valve.
qRA is extensively validated by the groups of Prof. Patrick Serruys and Prof. Carl Schulz. Validation studies have been performed in:
- Correlating with clinical endpoints to assess LVOT-AR cut-ff value of 0.17
- Comparing with MR Flow measurements
- Comparing with echocardiography measurements
- Comparing with visual classification of aortic regurgitation
- Phantom setup
Optimizing in cathlab workflow
To optimize in cathlab workflow the following studies been performed:
- Assessing overlap free projections to optimize analyzability of aortograms:
- Definition of technique for overlap free projection
- ASSESS-REGURGE. A multi-center trial to assess that protocolized planning optimizes analyzability of aortograms.
Clinical Trials reference: NCT03644784
- Using diastolic injections to reduce the amount of contast needed to perform qRA measurement.
Use in practice
CAAS A-Valve qRA has been used to assess:
- Acute performance of a novel Xeltis valve in a pre-clinical setting
- Comparison of 7 different TAVR valves